MISSION
A UNIQUE GROUP OF PEOPLE WORKING TOGETHER TO DO
UNIQUE THINGS.
WE ARE REPERTOIRE IMMUNE MEDICINEs™
We are Repertoire Immune Medicines – a Flagship Pioneering company working to unleash the remarkable power of the human immune system. We seek to harness the intrinsic ability of T cells to prevent and cure disease. Our mission is a challenging one, requiring a complex and multi-dimensional approach that integrates cutting-edge biology and sophisticated, novel technologies. We stand ready to meet this challenge with our unique platforms, world-class team and unparalleled network of researchers, clinicians, academics and entrepreneurs.
THE QUESTION
THAT STARTED IT ALL
Our journey began when scientists in Flagship Labs asked themselves a simple question: "What if we could decode the molecular signatures our
T cells respond to every day, and deploy these codes as medicines to prevent and cure disease?” Flagship applied its proprietary methodology – hypothesis development, testing and iteration – to explore this question, and Repertoire Immune Medicines was born.

Today, we have the talent, the technology, the insights, the capital and the determination to make this vision a reality.
OUR ROADMAP FROM CODES
TO CURES
Cures are our intended destination - codes are our departure point. We are proud to have brought together some of the most creative minds to help build a unique technology platform with the power to read the most fundamental codes of the immune system - namely the interaction of a T cell, via its T cell receptor (TCR), with its corresponding antigen and deliver these codes to patients in need.  At Repertoire Immune Medicines, we believe that these antigen - TCR codes hold the key to understanding health and disease. By analyzing human cells, we read the codes (DECODE) that will serve as the basis for new classes of medicines. 

We deliver these codes (DEPLOY) through industrialized T cell manufacturing with sophisticated product optimization and cytokine armoring to prime the tumor microenvironment. Our process delivers the codes to patients fast with optimal efficacy and safety. 

Our platforms (DECODE) also allows for unique experimental medicine approaches to identify the multi clonal expansion and reactivity in patients for progressive code refinement and product optimization to enhance or shape the most productive T cell clones in our prospective products. Our high-throughput platforms generates deep experimental data across millions of cells and thousands of samples and allows us to computationally deduce the most probable path from codes to cures to leverage the knowledge on a population basis. Our initial focus is immune oncology. Ultimately, we aspire to deliver a rich pipeline of preventive and curative medicines for any number of immunological diseases.